This dataset, markers_mouse_brain_df, is a data frame containing the top 1,000 marker genes for each of six major brain cell types (astrocytes, endothelial cells, microglia, neurons, oligodendrocytes, and OPCs) identified through meta-analysis of mouse brain gene expression data.
Usage
data(markers_mouse_brain_df)Format
A data frame with 5,430 observations and 2 variables:
- markers
Character: Gene symbol for cell-type specific marker
- cell
Character: Cell type classification (astrocytes/endothelial/microglia/neurons/oligodendrocytes/OPCs)
Source
Data taken from the BRETIGEA package version 1.0.3. Original study: Mckenzie AT, Wang M, Hauberg ME, et al. (2018) Brain Cell Type Specific Gene Expression and Co-expression Network Architectures. Scientific Reports, 8(1), 8868.
Details
The dataset name has been kept as 'markers_mouse_brain_df' to avoid confusion with other datasets in the R ecosystem. This naming convention helps distinguish this dataset as part of the NeuroDataSets package. The suffix 'df' indicates that the dataset is a data frame. The original content has not been modified.